COA Melanotan 1 (MT1) 10mgCertificate

Melanotan 1 (MT1) 10mg — Premium Research Peptide for Melanocortin Studies

Melanotan 1 (MT1), also known as afamelanotide, is a linear synthetic analog of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). Supplied in a convenient 10mg lyophilized format, MT1 is extensively used in peptide research focusing on melanocortin receptor binding, pigmentation pathways, and photoprotective mechanisms. This product is intended strictly for in vitro and laboratory research use only.

HPLC Melanotan 1 (MT1) 10mgCertificate

MS Melanotan 1 (MT1) 10mgCertificate

What Is Melanotan 1 (MT1)?

Melanotan 1 is a 13-amino acid linear peptide that was originally developed at the University of Arizona as part of research into natural sun protection alternatives. Unlike its cyclic counterpart Melanotan 2 (MT2), MT1 is a full-length peptide that more closely mirrors the structure of endogenous α-MSH. It acts primarily on the MC1R (melanocortin 1 receptor), stimulating melanogenesis — the biological process responsible for melanin production in skin cells.

MT1 has demonstrated a longer half-life compared to native α-MSH, making it a valuable research compound for studying sustained melanocortin receptor activity and its downstream physiological effects in controlled laboratory settings.

Mechanism of Action: How MT1 Interacts with Melanocortin Receptors

MT1 exerts its effects by binding to and activating melanocortin receptors, particularly MC1R, which is expressed on melanocytes. Upon receptor binding, MT1 triggers the cAMP signaling cascade, upregulating the enzyme tyrosinase and increasing the production of eumelanin — the dark, UV-protective form of melanin. Key research applications of this mechanism include:

• Photoprotection research — studying UV-induced DNA damage mitigation through enhanced melanin synthesis
• Skin pigmentation pathways — understanding genetic and biochemical determinants of skin color
• Erythropoietic protoporphyria (EPP) models — exploring light sensitivity and photoprotective strategies
• Inflammatory response studies — examining anti-inflammatory properties linked to melanocortin receptor activation

Product Specifications — Melanotan 1 10mg

Our Melanotan 1 is manufactured under strict quality control conditions to ensure consistency and reliability for research applications. Each vial contains:

• Peptide: Melanotan 1 (Afamelanotide) — Linear α-MSH Analog
• Quantity: 10mg per vial (lyophilized powder)
• Sequence: Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
• Purity: ≥98% (verified by HPLC analysis)
• Molecular Formula: C78H111N21O19S
• Molecular Weight: 1646.85 g/mol
• Storage: Lyophilized peptide stable at −20°C; in solution, store at 4°C for up to 7 days
• Appearance: White to off-white lyophilized powder
• Reconstitution: Bacteriostatic water or sterile water (for research use only)

Purity, Quality Assurance & Certificate of Analysis

Every batch of Melanotan 1 10mg undergoes rigorous third-party testing via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to confirm identity, purity, and potency. A Certificate of Analysis (CoA) is available for every batch upon request, ensuring full transparency and research-grade reliability. Our commitment to quality means that researchers can depend on consistent results across experiments.

Research Applications of Melanotan 1 (MT1)

MT1 is one of the most widely studied peptides in melanocortin research, with a growing body of preclinical literature exploring its diverse physiological roles. Documented research applications include:

Photoprotection & UV Damage Research

Studies have explored MT1’s potential to stimulate melanin production ahead of UV exposure, with afamelanotide gaining regulatory approval in several countries (including the EU and Australia) under the brand name Scenesse for the management of Erythropoietic Protoporphyria (EPP). Research institutions continue to investigate MT1 as a model compound for photoprotective peptide development and UV-induced carcinogenesis prevention.

Anti-Inflammatory & Immunomodulatory Studies

Beyond pigmentation, melanocortin receptors play a significant role in immune regulation. MT1 has been studied for its interaction with MC1R on immune cells, with research suggesting potential anti-inflammatory properties. Preclinical models have examined its effects on cytokine modulation, oxidative stress pathways, and inflammatory skin conditions, positioning MT1 as a valuable tool peptide for immunodermatology research.

Handling, Reconstitution & Research Disclaimer

Melanotan 1 10mg is supplied as a lyophilized powder and should be handled under sterile conditions. For reconstitution, bacteriostatic water is recommended. Once in solution, the peptide should be stored at 4°C and used within 7 days to maintain integrity. Always handle peptide solutions with appropriate PPE in a suitable laboratory environment.

Why Choose Our Melanotan 1 10mg for Your Research?

• Research-Grade Purity: ≥98% HPLC-verified purity in every batch
• Full Transparency: CoA available on request with each order
• Reliable Supply: Consistent stock with fast international dispatch
• Expert Support: Dedicated customer service for research and technical inquiries
• Secure Packaging: Vacuum-sealed, temperature-stable packaging for integrity during transit